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FAM124B has not been detected as a mutational cancer driver

FAM124B
Ensembl id ENSG00000124019
Mutated samples
Coding Sequence 36 (0.5%)
Protein Affecting 28 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FAM124B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 8 7 1.90
Breast carcinoma No 5 5 0.44
Lung squamous cell carcinoma No 4 4 2.30
Lung adenocarcinoma No 4 3 0.77
Serous ovarian adenocarcinoma No 2 2 0.63
Pancreas adenocarcinoma No 1 1 0.47
Uterine corpus endometrioid carcinoma No 1 1 0.43
Stomach adenocarcinoma No 3 1 0.62
Colorectal adenocarcinoma No 1 1 0.44
Head and neck squamous cell carcinoma No 3 1 0.27
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 1 1 0.68
Hepatocarcinoma No 1 0 0.00
Lower grade glioma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence