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EVC2 has not been detected as a mutational cancer driver

EVC2
Ensembl id ENSG00000173040
Mutated samples
Coding Sequence 114 (1.7%)
Protein Affecting 84 (1.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all EVC2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 22 16 4.34
Colorectal adenocarcinoma No 15 10 4.37
Lung squamous cell carcinoma No 11 9 5.17
Stomach adenocarcinoma No 11 8 4.97
Lung adenocarcinoma No 8 7 1.79
Head and neck squamous cell carcinoma No 6 6 1.60
Esophageal carcinoma No 9 6 4.11
Breast carcinoma No 6 5 0.44
Bladder carcinoma No 4 4 4.08
Small cell lung carcinoma No 3 3 4.35
Hepatocarcinoma No 2 2 2.22
Serous ovarian adenocarcinoma No 3 2 0.63
Prostate adenocarcinoma No 1 1 0.41
Neuroblastoma No 2 1 0.48
Uterine corpus endometrioid carcinoma No 3 1 0.43
Chronic lymphocytic leukemia No 3 1 0.34
Lower grade glioma No 1 1 0.59
Glioblastoma multiforme No 1 1 0.26
Renal clear cell carcinoma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence