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DISP1 has not been detected as a mutational cancer driver

DISP1
Ensembl id ENSG00000154309
Mutated samples
Coding Sequence 115 (1.7%)
Protein Affecting 84 (1.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all DISP1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 40 33 8.94
Lung adenocarcinoma No 8 6 1.53
Lung squamous cell carcinoma No 7 6 3.45
Uterine corpus endometrioid carcinoma No 7 6 2.61
Breast carcinoma No 7 5 0.44
Stomach adenocarcinoma No 8 4 2.48
Head and neck squamous cell carcinoma No 7 4 1.07
Renal clear cell carcinoma No 6 3 0.72
Chronic lymphocytic leukemia No 7 3 1.03
Colorectal adenocarcinoma No 3 3 1.31
Prostate adenocarcinoma No 3 2 0.82
Bladder carcinoma No 3 2 2.04
Small cell lung carcinoma No 2 2 2.90
Esophageal carcinoma No 2 2 1.37
Hepatocarcinoma No 2 1 1.11
Pancreas adenocarcinoma No 1 1 0.47
Glioblastoma multiforme No 1 1 0.26
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence