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DEDD has not been detected as a mutational cancer driver

DEDD
Ensembl id ENSG00000158796
Mutated samples
Coding Sequence 32 (0.5%)
Protein Affecting 11 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all DEDD gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Renal clear cell carcinoma No 5 2 0.48
Cutaneous melanoma No 4 2 0.54
Lung adenocarcinoma No 5 1 0.26
Breast carcinoma No 5 1 0.09
Neuroblastoma No 2 1 0.48
Uterine corpus endometrioid carcinoma No 4 1 0.43
Stomach adenocarcinoma No 1 1 0.62
Head and neck squamous cell carcinoma No 1 1 0.27
Glioblastoma multiforme No 1 1 0.26
Hepatocarcinoma No 2 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence