IntOGen - DAXX gene cancer mutations

DAXX is detected as a mutational cancer driver

DAXX reports

Methods
Mutation distribution

Gene details

DAXX
Ensembl ID ENSG00000204209 Transcript ID ENST00000266000 Protein ID ENSP00000266000
Cancer types where is driver 2 Cohorts where is driver 3 Mutated samples 22 Mutations 274
Mode of action Loss of function
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence