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CWH43 has not been detected as a mutational cancer driver

CWH43
Ensembl id ENSG00000109182
Mutated samples
Coding Sequence 108 (1.6%)
Protein Affecting 78 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CWH43 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 51 37 10.03
Lung adenocarcinoma No 11 8 2.05
Lung squamous cell carcinoma No 11 8 4.60
Breast carcinoma No 4 4 0.35
Small cell lung carcinoma No 4 4 5.80
Renal clear cell carcinoma No 4 3 0.72
Uterine corpus endometrioid carcinoma No 4 3 1.30
Stomach adenocarcinoma No 4 3 1.86
Head and neck squamous cell carcinoma No 4 2 0.53
Esophageal carcinoma No 2 2 1.37
Bladder carcinoma No 1 1 1.02
Non small cell lung carcinoma No 1 1 3.23
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 1 1 0.32
Prostate adenocarcinoma No 1 0 0.00
Hepatocarcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence