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CRNN has not been detected as a mutational cancer driver

CRNN
Ensembl id ENSG00000143536
Mutated samples
Coding Sequence 78 (1.1%)
Protein Affecting 58 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CRNN gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 29 18 4.88
Lung adenocarcinoma No 10 10 2.56
Breast carcinoma No 4 4 0.35
Stomach adenocarcinoma No 5 4 2.48
Uterine corpus endometrioid carcinoma No 4 3 1.30
Glioblastoma multiforme No 3 3 0.79
Lung squamous cell carcinoma No 3 2 1.15
Lower grade glioma No 2 2 1.18
Serous ovarian adenocarcinoma No 2 2 0.63
Small cell lung carcinoma No 2 2 2.90
Head and neck squamous cell carcinoma No 5 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Bladder carcinoma No 1 1 1.02
Thyroid carcinoma No 1 1 0.31
Neuroblastoma No 1 1 0.48
Colorectal adenocarcinoma No 1 1 0.44
Esophageal carcinoma No 2 1 0.68
Renal clear cell carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence