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COL6A6 has not been detected as a mutational cancer driver

COL6A6
Ensembl id ENSG00000206384
Mutated samples
Coding Sequence 265 (3.9%)
Protein Affecting 210 (3.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all COL6A6 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 80 58 15.72
Head and neck squamous cell carcinoma No 26 20 5.33
Lung adenocarcinoma No 27 19 4.86
Lung squamous cell carcinoma No 22 19 10.92
Breast carcinoma No 17 16 1.39
Renal clear cell carcinoma No 14 12 2.88
Stomach adenocarcinoma No 11 10 6.21
Bladder carcinoma No 11 9 9.18
Uterine corpus endometrioid carcinoma No 9 9 3.91
Colorectal adenocarcinoma No 7 6 2.62
Glioblastoma multiforme No 6 6 1.58
Serous ovarian adenocarcinoma No 8 5 1.58
Esophageal carcinoma No 8 5 3.42
Neuroblastoma No 3 3 1.43
Multiple myeloma No 3 3 4.35
Prostate adenocarcinoma No 3 2 0.82
Hepatocarcinoma No 3 2 2.22
Chronic lymphocytic leukemia No 2 2 0.69
Small cell lung carcinoma No 2 2 2.90
Pancreas adenocarcinoma No 2 1 0.47
Thyroid carcinoma No 1 1 0.31
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence