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CNTN6 has not been detected as a mutational cancer driver

CNTN6
Ensembl id ENSG00000134115
Mutated samples
Coding Sequence 188 (2.8%)
Protein Affecting 147 (2.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CNTN6 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 44 33 8.94
Esophageal carcinoma No 19 19 13.01
Breast carcinoma No 14 12 1.05
Lung squamous cell carcinoma No 15 11 6.32
Head and neck squamous cell carcinoma No 13 10 2.67
Lung adenocarcinoma No 11 9 2.30
Stomach adenocarcinoma No 12 8 4.97
Colorectal adenocarcinoma No 9 8 3.49
Uterine corpus endometrioid carcinoma No 7 7 3.04
Glioblastoma multiforme No 7 6 1.58
Prostate adenocarcinoma No 5 5 2.06
Bladder carcinoma No 5 5 5.10
Small cell lung carcinoma No 4 4 5.80
Renal clear cell carcinoma No 2 2 0.48
Chronic lymphocytic leukemia No 10 2 0.69
Hepatocarcinoma No 4 1 1.11
Acute myeloid leukemia No 1 1 0.51
Pancreas adenocarcinoma No 1 1 0.47
Neuroblastoma No 1 1 0.48
Non small cell lung carcinoma No 1 1 3.23
Serous ovarian adenocarcinoma No 1 1 0.32
Pylocytic astrocytoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence