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CLDN11 has not been detected as a mutational cancer driver

CLDN11
Ensembl id ENSG00000013297
Mutated samples
Coding Sequence 123 (1.8%)
Protein Affecting 15 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CLDN11 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 30 4 1.08
Lung adenocarcinoma No 17 3 0.77
Serous ovarian adenocarcinoma No 4 2 0.63
Hepatocarcinoma No 3 1 1.11
Acute myeloid leukemia No 1 1 0.51
Breast carcinoma No 7 1 0.09
Lung squamous cell carcinoma No 6 1 0.57
Uterine corpus endometrioid carcinoma No 8 1 0.43
Glioblastoma multiforme No 3 1 0.26
Prostate adenocarcinoma No 1 0 0.00
Bladder carcinoma No 2 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Renal clear cell carcinoma No 3 0 0.00
Chronic lymphocytic leukemia No 9 0 0.00
Multiple myeloma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Stomach adenocarcinoma No 7 0 0.00
Colorectal adenocarcinoma No 3 0 0.00
Head and neck squamous cell carcinoma No 13 0 0.00
Esophageal carcinoma No 2 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence