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CLCA2 has not been detected as a mutational cancer driver

CLCA2
Ensembl id ENSG00000137975
Mutated samples
Coding Sequence 64 (0.9%)
Protein Affecting 48 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CLCA2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 14 12 3.07
Cutaneous melanoma No 15 11 2.98
Lung squamous cell carcinoma No 4 4 2.30
Stomach adenocarcinoma No 4 3 1.86
Esophageal carcinoma No 3 3 2.05
Breast carcinoma No 4 2 0.17
Serous ovarian adenocarcinoma No 2 2 0.63
Colorectal adenocarcinoma No 4 2 0.87
Head and neck squamous cell carcinoma No 4 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Hepatocarcinoma No 2 1 1.11
Bladder carcinoma No 1 1 1.02
Medulloblastoma No 1 1 0.48
Pancreas adenocarcinoma No 1 1 0.47
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 1 1 0.26
Renal clear cell carcinoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence