CHD1L mutations in 7 cancer types possibly contribute to the detection of the gene in the PAN-cancer anlaysis:: Prostate adenocarcinoma, Lung adenocarcinoma, Lung squamous cell carcinoma, Cutaneous melanoma, Serous ovarian adenocarcinoma, Stomach adenocarcinoma, Small cell lung carcinoma

Ensembl id ENSG00000131778
Mutated samples
Coding Sequence 51 (0.8%)
Protein Affecting 44 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CHD1L gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma Yes 11 11 2.98
Stomach adenocarcinoma Yes 6 5 3.11
Lung adenocarcinoma Yes 4 3 0.77
Prostate adenocarcinoma Yes 2 2 0.82
Lung squamous cell carcinoma Yes 3 2 1.15
Serous ovarian adenocarcinoma Yes 3 2 0.63
Small cell lung carcinoma Yes 2 2 2.90
Breast carcinoma No 8 8 0.70
Head and neck squamous cell carcinoma No 6 5 1.33
Uterine corpus endometrioid carcinoma No 4 4 1.74
Chronic lymphocytic leukemia No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence