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CEP350 has not been detected as a mutational cancer driver

CEP350
Ensembl id ENSG00000135837
Mutated samples
Coding Sequence 138 (2.0%)
Protein Affecting 108 (1.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CEP350 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 33 26 7.05
Breast carcinoma No 13 13 1.13
Lung squamous cell carcinoma No 17 12 6.90
Head and neck squamous cell carcinoma No 14 10 2.67
Lung adenocarcinoma No 10 8 2.05
Bladder carcinoma No 7 5 5.10
Stomach adenocarcinoma No 5 5 3.11
Glioblastoma multiforme No 8 5 1.32
Uterine corpus endometrioid carcinoma No 7 4 1.74
Serous ovarian adenocarcinoma No 4 3 0.95
Colorectal adenocarcinoma No 3 3 1.31
Esophageal carcinoma No 3 3 2.05
Prostate adenocarcinoma No 2 2 0.82
Renal clear cell carcinoma No 2 2 0.48
Hepatocarcinoma No 2 1 1.11
Medulloblastoma No 2 1 0.48
Thyroid carcinoma No 1 1 0.31
Neuroblastoma No 1 1 0.48
Chronic lymphocytic leukemia No 2 1 0.34
Lower grade glioma No 1 1 0.59
Small cell lung carcinoma No 1 1 1.45
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence