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CEP170 has not been detected as a mutational cancer driver

CEP170
Ensembl id ENSG00000143702
Mutated samples
Coding Sequence 86 (1.3%)
Protein Affecting 69 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CEP170 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 17 12 3.25
Breast carcinoma No 10 9 0.78
Lung adenocarcinoma No 10 8 2.05
Head and neck squamous cell carcinoma No 10 8 2.13
Bladder carcinoma No 5 5 5.10
Lung squamous cell carcinoma No 6 5 2.87
Stomach adenocarcinoma No 5 5 3.11
Renal clear cell carcinoma No 4 4 0.96
Uterine corpus endometrioid carcinoma No 4 4 1.74
Prostate adenocarcinoma No 2 2 0.82
Colorectal adenocarcinoma No 2 2 0.87
Hepatocarcinoma No 1 1 1.11
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 1 1 0.32
Glioblastoma multiforme No 2 1 0.26
Esophageal carcinoma No 1 1 0.68
Acute myeloid leukemia No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Small cell lung carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence