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CENPE has not been detected as a mutational cancer driver

CENPE
Ensembl id ENSG00000138778
Mutated samples
Coding Sequence 130 (1.9%)
Protein Affecting 103 (1.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CENPE gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 33 28 7.59
Breast carcinoma No 12 12 1.05
Lung adenocarcinoma No 11 10 2.56
Lung squamous cell carcinoma No 10 9 5.17
Head and neck squamous cell carcinoma No 9 8 2.13
Small cell lung carcinoma No 8 6 8.70
Renal clear cell carcinoma No 5 5 1.20
Uterine corpus endometrioid carcinoma No 5 5 2.17
Bladder carcinoma No 8 4 4.08
Colorectal adenocarcinoma No 5 4 1.75
Glioblastoma multiforme No 5 4 1.06
Serous ovarian adenocarcinoma No 4 2 0.63
Esophageal carcinoma No 3 2 1.37
Pancreas adenocarcinoma No 2 1 0.47
Thyroid carcinoma No 1 1 0.31
Chronic lymphocytic leukemia No 2 1 0.34
Stomach adenocarcinoma No 3 1 0.62
Prostate adenocarcinoma No 2 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Multiple myeloma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence