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CD48 has not been detected as a mutational cancer driver

CD48
Ensembl id ENSG00000117091
Mutated samples
Coding Sequence 30 (0.4%)
Protein Affecting 20 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CD48 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 16 10 2.71
Lung adenocarcinoma No 3 3 0.77
Prostate adenocarcinoma No 3 2 0.82
Breast carcinoma No 2 2 0.17
Neuroblastoma No 1 1 0.48
Head and neck squamous cell carcinoma No 1 1 0.27
Esophageal carcinoma No 1 1 0.68
Bladder carcinoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence