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CD1B has not been detected as a mutational cancer driver

CD1B
Ensembl id ENSG00000158485
Mutated samples
Coding Sequence 69 (1.0%)
Protein Affecting 54 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CD1B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 25 20 5.42
Lung adenocarcinoma No 7 6 1.53
Lung squamous cell carcinoma No 7 6 3.45
Breast carcinoma No 5 5 0.44
Stomach adenocarcinoma No 5 4 2.48
Non small cell lung carcinoma No 4 3 9.68
Prostate adenocarcinoma No 2 2 0.82
Serous ovarian adenocarcinoma No 2 2 0.63
Head and neck squamous cell carcinoma No 3 2 0.53
Lower grade glioma No 1 1 0.59
Colorectal adenocarcinoma No 2 1 0.44
Glioblastoma multiforme No 2 1 0.26
Esophageal carcinoma No 2 1 0.68
Bladder carcinoma No 1 0 0.00
Acute myeloid leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence