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CATSPER4 has not been detected as a mutational cancer driver

CATSPER4
Ensembl id ENSG00000188782
Mutated samples
Coding Sequence 76 (1.1%)
Protein Affecting 33 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CATSPER4 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 25 11 2.98
Renal clear cell carcinoma No 8 4 0.96
Hepatocarcinoma No 2 2 2.22
Breast carcinoma No 6 2 0.17
Uterine corpus endometrioid carcinoma No 3 2 0.87
Small cell lung carcinoma No 2 2 2.90
Colorectal adenocarcinoma No 2 2 0.87
Glioblastoma multiforme No 3 2 0.53
Lung adenocarcinoma No 6 1 0.26
Acute myeloid leukemia No 1 1 0.51
Medulloblastoma No 2 1 0.48
Lung squamous cell carcinoma No 3 1 0.57
Stomach adenocarcinoma No 4 1 0.62
Head and neck squamous cell carcinoma No 3 1 0.27
Chronic lymphocytic leukemia No 1 0 0.00
Serous ovarian adenocarcinoma No 3 0 0.00
Esophageal carcinoma No 1 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence