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C1orf174 has not been detected as a mutational cancer driver

C1orf174
Ensembl id ENSG00000198912
Mutated samples
Coding Sequence 20 (0.3%)
Protein Affecting 9 (0.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all C1orf174 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 2 2 0.54
Stomach adenocarcinoma No 5 2 1.24
Lung adenocarcinoma No 1 1 0.26
Breast carcinoma No 1 1 0.09
Neuroblastoma No 1 1 0.48
Lower grade glioma No 1 1 0.59
Small cell lung carcinoma No 1 1 1.45
Prostate adenocarcinoma No 1 0 0.00
Hepatocarcinoma No 1 0 0.00
Lung squamous cell carcinoma No 1 0 0.00
Renal clear cell carcinoma No 3 0 0.00
Uterine corpus endometrioid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence