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C1orf112 has not been detected as a mutational cancer driver

C1orf112
Ensembl id ENSG00000000460
Mutated samples
Coding Sequence 183 (2.7%)
Protein Affecting 33 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all C1orf112 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 17 6 1.53
Breast carcinoma No 16 5 0.44
Cutaneous melanoma No 63 5 1.36
Renal clear cell carcinoma No 10 3 0.72
Uterine corpus endometrioid carcinoma No 7 3 1.30
Lung squamous cell carcinoma No 10 2 1.15
Medulloblastoma No 3 1 0.48
Thyroid carcinoma No 1 1 0.31
Neuroblastoma No 2 1 0.48
Serous ovarian adenocarcinoma No 6 1 0.32
Stomach adenocarcinoma No 11 1 0.62
Small cell lung carcinoma No 3 1 1.45
Colorectal adenocarcinoma No 1 1 0.44
Head and neck squamous cell carcinoma No 10 1 0.27
Glioblastoma multiforme No 7 1 0.26
Prostate adenocarcinoma No 1 0 0.00
Hepatocarcinoma No 2 0 0.00
Bladder carcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Lower grade glioma No 5 0 0.00
Esophageal carcinoma No 3 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence