IntOGen - BIRC6 gene cancer mutations

BIRC6 is detected as a mutational cancer driver

BIRC6 reports

Methods
Mutation distribution

Gene details

BIRC6
Ensembl ID ENSG00000115760 Transcript ID ENST00000421745 Protein ID ENSP00000393596
Cancer types where is driver 11 Cohorts where is driver 15 Mutated samples 143 Mutations 1,578
Mode of action Ambiguous
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence