IntOGen - BCL6 gene cancer mutations

BCL6 is detected as a mutational cancer driver

BCL6 reports

Methods
Mutation distribution

Gene details

BCL6
Ensembl ID ENSG00000113916 Transcript ID ENST00000406870 Protein ID ENSP00000384371
Cancer types where is driver 3 Cohorts where is driver 5 Mutated samples 32 Mutations 318
Mode of action Ambiguous
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence