IntOGen - BCL2L12 gene cancer mutations

BCL2L12 is detected as a mutational cancer driver

BCL2L12 reports

Methods
Mutation distribution

Gene details

BCL2L12
Ensembl ID ENSG00000126453 Transcript ID ENST00000616144 Protein ID ENSP00000482218
Cancer types where is driver 2 Cohorts where is driver 2 Mutated samples 32 Mutations 177
Mode of action Ambiguous
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence