IntOGen - BCL10 gene cancer mutations

BCL10 is detected as a mutational cancer driver

BCL10 reports

Methods
Mutation distribution

Gene details

BCL10
Ensembl ID ENSG00000142867 Transcript ID ENST00000648566 Protein ID ENSP00000498104
Cancer types where is driver 2 Cohorts where is driver 3 Mutated samples 10 Mutations 103
Mode of action Ambiguous
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence