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BCHE has not been detected as a mutational cancer driver

BCHE
Ensembl id ENSG00000114200
Mutated samples
Coding Sequence 88 (1.3%)
Protein Affecting 72 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all BCHE gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 16 14 3.58
Lung squamous cell carcinoma No 13 11 6.32
Cutaneous melanoma No 5 5 1.36
Breast carcinoma No 4 4 0.35
Uterine corpus endometrioid carcinoma No 4 4 1.74
Serous ovarian adenocarcinoma No 4 4 1.27
Colorectal adenocarcinoma No 4 4 1.75
Head and neck squamous cell carcinoma No 6 4 1.07
Esophageal carcinoma No 5 3 2.05
Bladder carcinoma No 2 2 2.04
Pancreas adenocarcinoma No 2 2 0.93
Renal clear cell carcinoma No 2 2 0.48
Non small cell lung carcinoma No 2 2 6.45
Stomach adenocarcinoma No 5 2 1.24
Small cell lung carcinoma No 3 2 2.90
Glioblastoma multiforme No 2 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Hepatocarcinoma No 2 1 1.11
Acute myeloid leukemia No 1 1 0.51
Multiple myeloma No 1 1 1.45
Acute lymphocytic leukemia No 1 1 0.82
Chronic lymphocytic leukemia No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence