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ATP13A3 has not been detected as a mutational cancer driver

ATP13A3
Ensembl id ENSG00000133657
Mutated samples
Coding Sequence 90 (1.3%)
Protein Affecting 50 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ATP13A3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 24 15 4.07
Head and neck squamous cell carcinoma No 10 6 1.60
Lung squamous cell carcinoma No 10 5 2.87
Lung adenocarcinoma No 5 3 0.77
Bladder carcinoma No 4 3 3.06
Uterine corpus endometrioid carcinoma No 4 3 1.30
Stomach adenocarcinoma No 7 3 1.86
Prostate adenocarcinoma No 4 2 0.82
Breast carcinoma No 5 2 0.17
Renal clear cell carcinoma No 2 2 0.48
Small cell lung carcinoma No 2 2 2.90
Lower grade glioma No 2 1 0.59
Serous ovarian adenocarcinoma No 1 1 0.32
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 2 1 0.68
Hepatocarcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Colorectal adenocarcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence