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ATF2 has not been detected as a mutational cancer driver

ATF2
Ensembl id ENSG00000115966
Mutated samples
Coding Sequence 34 (0.5%)
Protein Affecting 28 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ATF2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 6 6 1.53
Cutaneous melanoma No 9 6 1.63
Breast carcinoma No 3 3 0.26
Lung squamous cell carcinoma No 3 3 1.72
Uterine corpus endometrioid carcinoma No 2 2 0.87
Non small cell lung carcinoma No 2 2 6.45
Prostate adenocarcinoma No 1 1 0.41
Pancreas adenocarcinoma No 1 1 0.47
Renal clear cell carcinoma No 1 1 0.24
Chronic lymphocytic leukemia No 2 1 0.34
Stomach adenocarcinoma No 1 1 0.62
Acute lymphocytic leukemia No 1 1 0.82
Hepatocarcinoma No 1 0 0.00
Bladder carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence