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ARHGEF38 has not been detected as a mutational cancer driver

ARHGEF38
Ensembl id ENSG00000236699
Mutated samples
Coding Sequence 53 (0.8%)
Protein Affecting 16 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ARHGEF38 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Serous ovarian adenocarcinoma No 3 3 0.95
Lung adenocarcinoma No 5 2 0.51
Breast carcinoma No 7 2 0.17
Head and neck squamous cell carcinoma No 6 2 0.53
Medulloblastoma No 3 1 0.48
Lung squamous cell carcinoma No 3 1 0.57
Cutaneous melanoma No 7 1 0.27
Uterine corpus endometrioid carcinoma No 2 1 0.43
Stomach adenocarcinoma No 1 1 0.62
Colorectal adenocarcinoma No 2 1 0.44
Acute lymphocytic leukemia No 1 1 0.82
Prostate adenocarcinoma No 1 0 0.00
Bladder carcinoma No 3 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Multiple myeloma No 2 0 0.00
Small cell lung carcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
Esophageal carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence