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ADD2 has not been detected as a mutational cancer driver

ADD2
Ensembl id ENSG00000075340
Mutated samples
Coding Sequence 107 (1.6%)
Protein Affecting 69 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ADD2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 45 29 7.86
Esophageal carcinoma No 8 6 4.11
Lung adenocarcinoma No 8 4 1.02
Breast carcinoma No 6 4 0.35
Uterine corpus endometrioid carcinoma No 4 4 1.74
Colorectal adenocarcinoma No 5 3 1.31
Lung squamous cell carcinoma No 3 2 1.15
Renal clear cell carcinoma No 2 2 0.48
Serous ovarian adenocarcinoma No 3 2 0.63
Stomach adenocarcinoma No 2 2 1.24
Small cell lung carcinoma No 2 2 2.90
Head and neck squamous cell carcinoma No 3 2 0.53
Glioblastoma multiforme No 2 2 0.53
Hepatocarcinoma No 1 1 1.11
Bladder carcinoma No 1 1 1.02
Medulloblastoma No 2 1 0.48
Multiple myeloma No 1 1 1.45
Lower grade glioma No 1 1 0.59
Pancreas adenocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 5 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence