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ACTR3 has not been detected as a mutational cancer driver

ACTR3
Ensembl id ENSG00000115091
Mutated samples
Coding Sequence 14 (0.2%)
Protein Affecting 6 (0.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ACTR3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 2 2 0.54
Prostate adenocarcinoma No 1 1 0.41
Bladder carcinoma No 1 1 1.02
Medulloblastoma No 1 1 0.48
Esophageal carcinoma No 1 1 0.68
Lung adenocarcinoma No 2 0 0.00
Lung squamous cell carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Lower grade glioma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Stomach adenocarcinoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence