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ABI2 has not been detected as a mutational cancer driver

ABI2
Ensembl id ENSG00000138443
Mutated samples
Coding Sequence 66 (1.0%)
Protein Affecting 23 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ABI2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 13 5 1.36
Lung adenocarcinoma No 7 3 0.77
Hepatocarcinoma No 5 2 2.22
Breast carcinoma No 5 2 0.17
Renal clear cell carcinoma No 4 2 0.48
Thyroid carcinoma No 3 2 0.62
Stomach adenocarcinoma No 4 2 1.24
Head and neck squamous cell carcinoma No 6 2 0.53
Bladder carcinoma No 2 1 1.02
Multiple myeloma No 1 1 1.45
Glioblastoma multiforme No 2 1 0.26
Prostate adenocarcinoma No 2 0 0.00
Medulloblastoma No 1 0 0.00
Lung squamous cell carcinoma No 2 0 0.00
Uterine corpus endometrioid carcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Serous ovarian adenocarcinoma No 2 0 0.00
Small cell lung carcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Esophageal carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence