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TYRP1 has not been detected as a mutational cancer driver in this cancer type

Cutaneous melanoma
Projects 2
369 Samples
Coding sequence mutations (CSMs)
in driver genes 4035
in all genes 413513
Protein affecting mutations (PAMs)
in driver genes 2994
in all genes 167055
TYRP1
Ensembl id ENSG00000107165
Mutated samples
Coding Sequence 12 (3.3%)
Protein Affecting 12 (3.3%)
Mode of action Unclassified
Known driver No
Project Signals
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated Cutaneous melanoma projects in all TYRP1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Project Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Skin cutaneous melanoma TCGA obtained from Synapse No 7 7 1.90
Skin cutaneous melanoma BROAD obtained from Alexandrov No 5 5 1.36
The mutations needle plot shows the distribution of the observed TYRP1 cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence Driver classification