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TGFBR2 mutations in 1 Lung squamous cell carcinoma project possibly contribute to the detection of the gene in the PAN-cancer anlaysis:

Lung squamous cell carcinoma
Projects 1
174 Samples
Coding sequence mutations (CSMs)
in driver genes 1013
in all genes 80088
Protein affecting mutations (PAMs)
in driver genes 859
in all genes 43317
TGFBR2
Ensembl id ENSG00000163513
Mutated samples
Coding Sequence 5 (2.9%)
Protein Affecting 3 (1.7%)
Mode of action Loss of function
Known driver No
Project Signals
PAN
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated Lung squamous cell carcinoma projects in all TGFBR2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Project Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung squamous cell carcinoma TCGA Yes 5 3 1.72
The mutations needle plot shows the distribution of the observed TGFBR2 cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence Driver classification