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SOS1 has not been detected as a mutational cancer driver in this cancer type

Lung squamous cell carcinoma
Projects 1
174 Samples
Coding sequence mutations (CSMs)
in driver genes 1013
in all genes 80088
Protein affecting mutations (PAMs)
in driver genes 859
in all genes 43317
SOS1
Ensembl id ENSG00000115904
Mutated samples
Coding Sequence 10 (5.7%)
Protein Affecting 10 (5.7%)
Mode of action Activating
Known driver No
Project Signals
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated Lung squamous cell carcinoma projects in all SOS1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Project Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung squamous cell carcinoma TCGA No 10 10 5.75
The mutations needle plot shows the distribution of the observed SOS1 cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence Driver classification