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HIST2H3D has not been detected as a mutational cancer driver

HIST2H3D
Ensembl id ENSG00000183598
Mutated samples
Coding Sequence 42 (0.6%)
Protein Affecting 12 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all HIST2H3D gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Head and neck squamous cell carcinoma No 8 3 0.80
Lung adenocarcinoma No 4 1 0.26
Breast carcinoma No 4 1 0.09
Lung squamous cell carcinoma No 6 1 0.57
Renal clear cell carcinoma No 1 1 0.24
Thyroid carcinoma No 2 1 0.31
Cutaneous melanoma No 6 1 0.27
Uterine corpus endometrioid carcinoma No 3 1 0.43
Stomach adenocarcinoma No 2 1 0.62
Glioblastoma multiforme No 1 1 0.26
Prostate adenocarcinoma No 1 0 0.00
Bladder carcinoma No 2 0 0.00
Neuroblastoma No 1 0 0.00
Lower grade glioma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence