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HIST2H2BE has not been detected as a mutational cancer driver

HIST2H2BE
Ensembl id ENSG00000184678
Mutated samples
Coding Sequence 89 (1.3%)
Protein Affecting 22 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all HIST2H2BE gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 14 4 0.35
Lung squamous cell carcinoma No 7 3 1.72
Lung adenocarcinoma No 15 2 0.51
Bladder carcinoma No 3 2 2.04
Cutaneous melanoma No 10 2 0.54
Serous ovarian adenocarcinoma No 4 2 0.63
Head and neck squamous cell carcinoma No 8 2 0.53
Prostate adenocarcinoma No 2 1 0.41
Chronic lymphocytic leukemia No 2 1 0.34
Lower grade glioma No 2 1 0.59
Small cell lung carcinoma No 1 1 1.45
Diffuse B cell lymphoma No 2 1 4.35
Hepatocarcinoma No 2 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Renal clear cell carcinoma No 3 0 0.00
Thyroid carcinoma No 2 0 0.00
Uterine corpus endometrioid carcinoma No 3 0 0.00
Multiple myeloma No 1 0 0.00
Stomach adenocarcinoma No 5 0 0.00
Esophageal carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence