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FANCA has not been detected as a mutational cancer driver in this cancer type

Chronic lymphocytic leukemia
Projects 2
290 Samples
Coding sequence mutations (CSMs)
in driver genes 280
in all genes 49201
Protein affecting mutations (PAMs)
in driver genes 213
in all genes 4046
FANCA
Ensembl id ENSG00000187741
Mutated samples
Coding Sequence 2 (0.7%)
Protein Affecting 1 (0.3%)
Mode of action Unclassified
Known driver No
Project Signals
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated Chronic lymphocytic leukemia projects in all FANCA gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Project Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Chronic Lymphocytic Leukemia Broad No 2 1 0.34
The mutations needle plot shows the distribution of the observed FANCA cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence Driver classification