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CASP8 mutations in 1 Stomach adenocarcinoma project possibly contribute to the detection of the gene in the PAN-cancer anlaysis:

Stomach adenocarcinoma
Projects 2
161 Samples
Coding sequence mutations (CSMs)
in driver genes 1061
in all genes 79369
Protein affecting mutations (PAMs)
in driver genes 869
in all genes 37552
CASP8
Ensembl id ENSG00000064012
Mutated samples
Coding Sequence 6 (3.7%)
Protein Affecting 5 (3.1%)
Mode of action Loss of function
Known driver No
Project Signals
PAN
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated Stomach adenocarcinoma projects in all CASP8 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Project Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Stomach cancer TCGA obtained from Synapse Yes 6 5 3.11
The mutations needle plot shows the distribution of the observed CASP8 cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence Driver classification