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APC mutations in 1 Hepatocarcinoma project possibly contribute to the detection of the gene in the PAN-cancer anlaysis:

Hepatocarcinoma
Projects 2
90 Samples
Coding sequence mutations (CSMs)
in driver genes 151
in all genes 28172
Protein affecting mutations (PAMs)
in driver genes 104
in all genes 4873
APC
Ensembl id ENSG00000134982
Mutated samples
Coding Sequence 3 (3.3%)
Protein Affecting 2 (2.2%)
Mode of action Loss of function
Known driver Yes
Project Signals
PAN
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated Hepatocarcinoma projects in all APC gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Project Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Liver Cancer ICGC obtained from AlexandrovEtAl Yes 3 2 2.22
The mutations needle plot shows the distribution of the observed APC cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence Driver classification