Mutations

Search mutations, genes and pathways involved in tumorigenesis across 4,623 cancer genomes/exomes from 13 cancer sites.

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Analyze somatic mutations in a cohort of tumors to identify drivers and compare the results with accumulated knowledge in IntOGen.

Analyze the somatic mutations detected in the tumor of an individual patient and rank them according to their likely implication in the cancer phenotype.

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TCGA

Mutations and driver genes portal of data from the TCGA Pan-Cancer project. Search for mutations observed in 3205 tumors from 12 cancer types, their predicted functional impact and the evidences of genes with signals of positive selection pointing to cancer driver genes.

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Arrays

Search genes and pathways affected by expression and copy number changes in tumors across projects and cancer types.

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News

2013/10/27:  IntOGen-mutations analysis pipeline 2.4.0 released

2013/09/27:  The Cancer Genome Atlas Pan-Cancer Project

2013/09/25:  Chromatin maintenance and cancer

2013/09/16:  IntOGen-mutations: the analysis of cancer genomes published in Nature Methods

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About

IntOGen is developed by the Biomedical Genomics Group, a research group integrated in the Research Unit on Biomedical Informatics (GRIB) of the University Pompeu Fabra (UPF). The lab is located in the Biomedical Research Park in Barcelona (PRBB).