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149 mutational cancer drivers have been detected in this of Uterine corpus endometrioid carcinoma (UCEC) project from The Cancer Genome Atlas. The most mutated drivers are: PTEN, PIK3CA, PIK3R1, ARID1A, CTNNB1, etc.



Uterine corpus endometrioid carcinoma TCGA
UCEC Uterine corpus endometrioid carcinoma
230 Samples
Driver / Mut. genes149 / 20737
The Cancer Genome Atlas
Coding sequence mutations (CSMs)
in driver genes 1784
in all genes 68806
Protein affecting mutations (PAMs)
in driver genes 1591
in all genes 34136
This driver cloud represents the most recurrently mutated cancer driver genes in the Uterine corpus endometrioid carcinoma TCGA dataset. The size of the gene symbol is relative to the count of samples with PAMs.
This plot shows the most recurrently mutated cancer driver genes in the Uterine corpus endometrioid carcinoma TCGA dataset. Each bar of the histogram indicates the amount of samples with PAMs.

Gene symbol Ensembl id Driver class Mutated samples % Mutated samples
PTEN ENSG00000171862 146 143 62.17
PIK3CA ENSG00000121879 121 115 50.00
PIK3R1 ENSG00000145675 71 52 22.61
ARID1A ENSG00000117713 71 67 29.13
CTNNB1 ENSG00000168036 66 65 28.26
TP53 ENSG00000141510 66 61 26.52
KRAS ENSG00000133703 47 46 20.00
CTCF ENSG00000102974 38 38 16.52
ZFHX3 ENSG00000140836 32 29 12.61
FBXW7 ENSG00000109670 27 27 11.74
RPL22 ENSG00000116251 27 25 10.87
ARHGAP35 ENSG00000160007 24 23 10.00
ARID5B ENSG00000150347 24 22 9.57
FGFR2 ENSG00000066468 25 24 10.43
CHD4 ENSG00000111642 25 23 10.00
PPP2R1A ENSG00000105568 20 20 8.70
ANK3 ENSG00000151150 18 16 6.96
MGA ENSG00000174197 16 14 6.09
ATM ENSG00000149311 16 14 6.09
ATR ENSG00000175054 17 16 6.96
SPOP ENSG00000121067 15 15 6.52
CHD3 ENSG00000170004 14 13 5.65
INPPL1 ENSG00000165458 13 13 5.65
ERBB3 ENSG00000065361 11 11 4.78
EP300 ENSG00000100393 13 12 5.22
CCND1 ENSG00000110092 13 9 3.91
MAP3K1 ENSG00000095015 8 8 3.48
INPP4A ENSG00000040933 9 9 3.91
FOXA2 ENSG00000125798 11 11 4.78
CUX1 ENSG00000257923 12 11 4.78
NFE2L2 ENSG00000116044 12 12 5.22
MYH10 ENSG00000133026 9 9 3.91
DICER1 ENSG00000100697 9 9 3.91
BAZ2B ENSG00000123636 11 11 4.78
PRPF8 ENSG00000174231 11 11 4.78
ARAP3 ENSG00000120318 10 8 3.48
MAX ENSG00000125952 10 6 2.61
SMC1A ENSG00000072501 10 10 4.35
ARHGEF6 ENSG00000129675 8 7 3.04
PLXNB2 ENSG00000196576 9 9 3.91
CTNND1 ENSG00000198561 9 9 3.91
NRAS ENSG00000213281 9 6 2.61
NUP93 ENSG00000102900 8 8 3.48
ACACA ENSG00000132142 9 9 3.91
SEC31A ENSG00000138674 6 6 2.61
ALK ENSG00000171094 8 8 3.48
ING1 ENSG00000153487 8 7 3.04
PGR ENSG00000082175 8 6 2.61
MLH3 ENSG00000119684 6 5 2.17
ZMYM2 ENSG00000121741 8 8 3.48
FAM123B ENSG00000184675 8 8 3.48
AXIN1 ENSG00000103126 7 7 3.04
PLCG1 ENSG00000124181 7 7 3.04
TFDP1 ENSG00000198176 7 7 3.04
SOX17 ENSG00000164736 7 7 3.04
ACTG1 ENSG00000184009 6 6 2.61
ROBO2 ENSG00000185008 6 6 2.61
DEPDC1B ENSG00000035499 5 5 2.17
DHX35 ENSG00000101452 5 5 2.17
NEDD4L ENSG00000049759 5 5 2.17
MLH1 ENSG00000076242 11 3 1.30
WIPF1 ENSG00000115935 4 3 1.30
FUBP1 ENSG00000162613 7 3 1.30
GPS2 ENSG00000132522 6 3 1.30
STIP1 ENSG00000168439 5 3 1.30
PCDH18 ENSG00000189184 5 3 1.30
ATIC ENSG00000138363 5 2 0.87
DIS3 ENSG00000083520 4 2 0.87
PPP2R5C ENSG00000078304 4 3 1.30
DHX15 ENSG00000109606 5 3 1.30
MAP2K4 ENSG00000065559 5 3 1.30
ZNF814 ENSG00000204514 5 2 0.87
NCOR1 ENSG00000141027 5 3 1.30
EIF4A2 ENSG00000156976 5 3 1.30
RBM5 ENSG00000003756 3 2 0.87
SMAD2 ENSG00000175387 4 3 1.30
CUL1 ENSG00000055130 4 3 1.30
PTPN11 ENSG00000179295 4 2 0.87
KDM6A ENSG00000147050 4 2 0.87
TGFBR2 ENSG00000163513 4 3 1.30
FLT3 ENSG00000122025 4 2 0.87
HGF ENSG00000019991 4 3 1.30
CAPN7 ENSG00000131375 3 2 0.87
SUZ12 ENSG00000178691 4 3 1.30
ZFP36L2 ENSG00000152518 4 3 1.30
MKL1 ENSG00000196588 4 2 0.87
AKT1 ENSG00000142208 4 3 1.30
MET ENSG00000105976 4 3 1.30
TP53BP1 ENSG00000067369 4 3 1.30
BCLAF1 ENSG00000029363 3 3 1.30
GPSM2 ENSG00000121957 3 2 0.87
RBBP7 ENSG00000102054 3 2 0.87
CLOCK ENSG00000134852 3 3 1.30
TBL1XR1 ENSG00000177565 3 3 1.30
NDRG1 ENSG00000104419 3 3 1.30
MUC20 ENSG00000176945 3 2 0.87
CLTC ENSG00000141367 3 2 0.87
RUNX1 ENSG00000159216 3 3 1.30
IDH1 ENSG00000138413 3 2 0.87
TBX3 ENSG00000135111 3 3 1.30
CHEK2 ENSG00000183765 3 3 1.30
ACTB ENSG00000075624 3 3 1.30
KLF4 ENSG00000136826 3 3 1.30
CARM1 ENSG00000142453 3 2 0.87
PRRX1 ENSG00000116132 3 3 1.30
NCF2 ENSG00000116701 3 3 1.30
ZC3H11A ENSG00000058673 3 2 0.87
DNMT3A ENSG00000119772 3 3 1.30
G3BP2 ENSG00000138757 3 3 1.30
CAT ENSG00000121691 3 2 0.87
FXR1 ENSG00000114416 3 3 1.30
BRCA1 ENSG00000012048 3 2 0.87
EIF2C3 ENSG00000126070 3 3 1.30
PIK3R3 ENSG00000117461 3 2 0.87
CSNK1G3 ENSG00000151292 3 3 1.30
EIF4G1 ENSG00000114867 3 3 1.30
SYNCRIP ENSG00000135316 3 3 1.30
MYB ENSG00000118513 3 2 0.87
PHF6 ENSG00000156531 3 3 1.30
RAD21 ENSG00000164754 3 2 0.87
HDAC3 ENSG00000171720 3 2 0.87
SHMT1 ENSG00000176974 3 3 1.30
EGFR ENSG00000146648 3 3 1.30
CHD9 ENSG00000177200 3 3 1.30
ARNTL ENSG00000133794 3 3 1.30
CNOT4 ENSG00000080802 3 2 0.87
EIF2AK3 ENSG00000172071 2 2 0.87
IREB2 ENSG00000136381 2 2 0.87
CAST ENSG00000153113 2 2 0.87
BRAF ENSG00000157764 2 2 0.87
RPL5 ENSG00000122406 2 2 0.87
BMPR2 ENSG00000204217 2 2 0.87
RHEB ENSG00000106615 2 2 0.87
U2AF1 ENSG00000160201 2 2 0.87
PPP2R5A ENSG00000066027 2 2 0.87
EIF1AX ENSG00000173674 2 2 0.87
GNAI1 ENSG00000127955 2 2 0.87
RTN4 ENSG00000115310 2 2 0.87
MED17 ENSG00000042429 2 2 0.87
NF2 ENSG00000186575 2 2 0.87
RAD23B ENSG00000119318 2 2 0.87
SRGAP3 ENSG00000196220 2 2 0.87
CDKN1B ENSG00000111276 2 2 0.87
ATF1 ENSG00000123268 2 2 0.87
VHL ENSG00000134086 2 2 0.87
NR2F2 ENSG00000185551 2 2 0.87
NCKAP1 ENSG00000061676 2 2 0.87
AHR ENSG00000106546 2 2 0.87
FAS ENSG00000026103 2 2 0.87