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BRCA1 is detected as a mutational cancer driver

BRCA1 reports

Gene details
BRCA1
Ensembl ID ENSG00000012048
Transcript ID ENST00000471181
Protein ID ENSP00000418960
Cancer types where is driver 4
Cohorts where is driver 9
Mutated samples 88
Mutations 624
Mode of action Ambiguous
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence