NOTCH1 is detected as a mutational cancer driver
NOTCH1 reports
Gene details
NOTCH1 |
---|
Ensembl ID
ENSG00000148400
Transcript ID ENST00000651671 Protein ID ENSP00000498587 |
Cancer types where is driver
24
Cohorts where is driver 39 Mutated samples 598 Mutations 1,524 |
Mode of action Ambiguous |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
---|
In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
HNSC (Head and Neck Squamous Cell Carcinoma) | 22986 | 800 | 3.48 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
---|