IntOGen - RPL22 gene cancer mutations

RPL22 is detected as a mutational cancer driver

RPL22 reports

Methods
Mutation distribution

Gene details

RPL22
Ensembl ID ENSG00000116251 Transcript ID ENST00000234875 Protein ID ENSP00000346088
Cancer types where is driver 1 Cohorts where is driver 1 Mutated samples 3 Mutations 169
Mode of action Loss of function
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence