EZH2 is detected as a mutational cancer driver
EZH2 reports
Gene details
EZH2 |
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Ensembl ID
ENSG00000106462
Transcript ID ENST00000320356 Protein ID ENSP00000320147 |
Cancer types where is driver
7
Cohorts where is driver 12 Mutated samples 97 Mutations 361 |
Mode of action Ambiguous |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
DLBCL (Diffuse Large B-Cell Lymphoma, NOS) | 6750 | 20 | 0.30 |
LY (Lymphoid Neoplasm) | 6750 | 14 | 0.21 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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