RB1 is detected as a mutational cancer driver
RB1 reports
Gene details
RB1 |
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Ensembl ID
ENSG00000139687
Transcript ID ENST00000267163 Protein ID ENSP00000267163 |
Cancer types where is driver
24
Cohorts where is driver 62 Mutated samples 637 Mutations 1,266 |
Mode of action Ambiguous |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
BLCA (Bladder Urothelial Carcinoma) | 8343 | 516 | 6.18 |
BRCA (Invasive Breast Carcinoma) | 8343 | 422 | 5.06 |
GBM (Glioblastoma Multiforme) | 8343 | 422 | 5.06 |
HC (Hepatocellular Carcinoma) | 8343 | 516 | 6.18 |
LUNG_CANCER (Lung) | 8343 | 485 | 5.81 |
CM (Melanoma) | 8343 | 516 | 6.18 |
SCLC (Small Cell Lung Cancer) | 8343 | 516 | 6.18 |
SARC (Soft Tissue) | 8343 | 434 | 5.20 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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