FBXW7 is detected as a mutational cancer driver
FBXW7 reports
Gene details
FBXW7 |
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Ensembl ID
ENSG00000109670
Transcript ID ENST00000603548 Protein ID ENSP00000474725 |
Cancer types where is driver
22
Cohorts where is driver 43 Mutated samples 497 Mutations 844 |
Mode of action Ambiguous |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
CESC (Cervical Squamous Cell Carcinoma) | 6354 | 1030 | 16.21 |
COREAD (Colorectal Adenocarcinoma) | 6354 | 591 | 9.30 |
UCEC (Endometrial Carcinoma) | 6354 | 500 | 7.87 |
UCS (Uterine Carcinosarcoma/Uterine Malignant Mixed Mullerian Tumor) | 6354 | 225 | 3.54 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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