Top

TCF7L2 is detected as a mutational cancer driver

TCF7L2 reports

Gene details
TCF7L2
Ensembl ID ENSG00000148737
Transcript ID ENST00000627217
Protein ID ENSP00000486891
Cancer types where is driver 4
Cohorts where is driver 8
Mutated samples 131
Mutations 369
Mode of action Ambiguous
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence