SF3B1 is detected as a mutational cancer driver
SF3B1 reports
Gene details
SF3B1 |
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Ensembl ID
ENSG00000115524
Transcript ID ENST00000335508 Protein ID ENSP00000335321 |
Cancer types where is driver
14
Cohorts where is driver 25 Mutated samples 275 Mutations 726 |
Mode of action Ambiguous |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
BRCA (Invasive Breast Carcinoma) | 11727 | 1011 | 8.62 |
CLL (Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma) | 11727 | 529 | 4.51 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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