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CHEK2 is detected as a mutational cancer driver

CHEK2 reports

Gene details
CHEK2
Ensembl ID ENSG00000183765
Transcript ID ENST00000382580
Protein ID ENSP00000372023
Cancer types where is driver 3
Cohorts where is driver 3
Mutated samples 12
Mutations 225
Mode of action Ambiguous
Known driver False
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence